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Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy
Today, nanotechnology plays a vital role in biomedical applications, especially for the diagnosis and treatment of various diseases. Among the many different types of fabricated nanoparticles, magnetic metal oxide nanoparticles stand out as unique and useful tools for biomedical applications, becaus...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452369/ https://www.ncbi.nlm.nih.gov/pubmed/26078971 http://dx.doi.org/10.1155/2015/959175 |
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author | Uthaman, Saji Lee, Sang Joon Cherukula, Kondareddy Cho, Chong-Su Park, In-Kyu |
author_facet | Uthaman, Saji Lee, Sang Joon Cherukula, Kondareddy Cho, Chong-Su Park, In-Kyu |
author_sort | Uthaman, Saji |
collection | PubMed |
description | Today, nanotechnology plays a vital role in biomedical applications, especially for the diagnosis and treatment of various diseases. Among the many different types of fabricated nanoparticles, magnetic metal oxide nanoparticles stand out as unique and useful tools for biomedical applications, because of their imaging characteristics and therapeutic properties such as drug and gene carriers. Polymer-coated magnetic particles are currently of particular interest to investigators in the fields of nanobiomedicine and fundamental biomaterials. Theranostic magnetic nanoparticles that are encapsulated or coated with polymers not only exhibit imaging properties in response to stimuli, but also can efficiently deliver various drugs and therapeutic genes. Even though a large number of polymer-coated magnetic nanoparticles have been fabricated over the last decade, most of these have only been used for imaging purposes. The focus of this review is on polysaccharide-coated magnetic nanoparticles used for imaging and gene delivery. |
format | Online Article Text |
id | pubmed-4452369 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-44523692015-06-15 Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy Uthaman, Saji Lee, Sang Joon Cherukula, Kondareddy Cho, Chong-Su Park, In-Kyu Biomed Res Int Review Article Today, nanotechnology plays a vital role in biomedical applications, especially for the diagnosis and treatment of various diseases. Among the many different types of fabricated nanoparticles, magnetic metal oxide nanoparticles stand out as unique and useful tools for biomedical applications, because of their imaging characteristics and therapeutic properties such as drug and gene carriers. Polymer-coated magnetic particles are currently of particular interest to investigators in the fields of nanobiomedicine and fundamental biomaterials. Theranostic magnetic nanoparticles that are encapsulated or coated with polymers not only exhibit imaging properties in response to stimuli, but also can efficiently deliver various drugs and therapeutic genes. Even though a large number of polymer-coated magnetic nanoparticles have been fabricated over the last decade, most of these have only been used for imaging purposes. The focus of this review is on polysaccharide-coated magnetic nanoparticles used for imaging and gene delivery. Hindawi Publishing Corporation 2015 2015-05-19 /pmc/articles/PMC4452369/ /pubmed/26078971 http://dx.doi.org/10.1155/2015/959175 Text en Copyright © 2015 Saji Uthaman et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Uthaman, Saji Lee, Sang Joon Cherukula, Kondareddy Cho, Chong-Su Park, In-Kyu Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy |
title | Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy |
title_full | Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy |
title_fullStr | Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy |
title_full_unstemmed | Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy |
title_short | Polysaccharide-Coated Magnetic Nanoparticles for Imaging and Gene Therapy |
title_sort | polysaccharide-coated magnetic nanoparticles for imaging and gene therapy |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452369/ https://www.ncbi.nlm.nih.gov/pubmed/26078971 http://dx.doi.org/10.1155/2015/959175 |
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