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Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study

Purpose. The object of this study was to investigate the role of the suture stent regarding its impact on reduction of intraocular pressure (IOP) in canaloplasty based on the distension of the inner wall of Schlemm's canal. Methods. Nineteen glaucoma patients who underwent canaloplasty with suc...

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Autores principales: Brandao, Livia M., Schötzau, Andreas, Grieshaber, Matthias C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452487/
https://www.ncbi.nlm.nih.gov/pubmed/26078874
http://dx.doi.org/10.1155/2015/457605
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author Brandao, Livia M.
Schötzau, Andreas
Grieshaber, Matthias C.
author_facet Brandao, Livia M.
Schötzau, Andreas
Grieshaber, Matthias C.
author_sort Brandao, Livia M.
collection PubMed
description Purpose. The object of this study was to investigate the role of the suture stent regarding its impact on reduction of intraocular pressure (IOP) in canaloplasty based on the distension of the inner wall of Schlemm's canal. Methods. Nineteen glaucoma patients who underwent canaloplasty with successful positioning of the tensioning suture were included. The measurements were analyzed using linear mixed models, with the means adjusted to IOP, age, cup-to-disc ratio, and time of follow-up. Results. Mean follow-up time was 27.6 months (SD 10.5). Mean intraocular pressure (IOP) was 24.6 mmHg (SD 5.29), 13.8 (SD 2.65), and 14.5 (SD 0.71) before surgery, at 12 months, and at 36 months after surgery, respectively. 57.9% of patients had no medication at last evaluation. Differences and variations of measurements between the devices over a time of 12 months were not significant (p = 0.15 to 0.98). Some angles of distension associated with the suture stent inside SC were predictive for IOP reduction (p < 0.03 to < 0.001), but not for final IOP (p = 0.64 to 0.96). Conclusion. The angles of the inner wall of Schlemm's canal generated by the suture stent were comparable between OCT and UBM and did not change significantly over time. There was a tendency towards a greater distension of Schlemm's canal, when the difference was larger between pre- and postoperative IOP, suggesting the tensioning suture may contribute to IOP reduction.
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spelling pubmed-44524872015-06-15 Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study Brandao, Livia M. Schötzau, Andreas Grieshaber, Matthias C. J Ophthalmol Research Article Purpose. The object of this study was to investigate the role of the suture stent regarding its impact on reduction of intraocular pressure (IOP) in canaloplasty based on the distension of the inner wall of Schlemm's canal. Methods. Nineteen glaucoma patients who underwent canaloplasty with successful positioning of the tensioning suture were included. The measurements were analyzed using linear mixed models, with the means adjusted to IOP, age, cup-to-disc ratio, and time of follow-up. Results. Mean follow-up time was 27.6 months (SD 10.5). Mean intraocular pressure (IOP) was 24.6 mmHg (SD 5.29), 13.8 (SD 2.65), and 14.5 (SD 0.71) before surgery, at 12 months, and at 36 months after surgery, respectively. 57.9% of patients had no medication at last evaluation. Differences and variations of measurements between the devices over a time of 12 months were not significant (p = 0.15 to 0.98). Some angles of distension associated with the suture stent inside SC were predictive for IOP reduction (p < 0.03 to < 0.001), but not for final IOP (p = 0.64 to 0.96). Conclusion. The angles of the inner wall of Schlemm's canal generated by the suture stent were comparable between OCT and UBM and did not change significantly over time. There was a tendency towards a greater distension of Schlemm's canal, when the difference was larger between pre- and postoperative IOP, suggesting the tensioning suture may contribute to IOP reduction. Hindawi Publishing Corporation 2015 2015-05-19 /pmc/articles/PMC4452487/ /pubmed/26078874 http://dx.doi.org/10.1155/2015/457605 Text en Copyright © 2015 Livia M. Brandao et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Brandao, Livia M.
Schötzau, Andreas
Grieshaber, Matthias C.
Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study
title Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study
title_full Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study
title_fullStr Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study
title_full_unstemmed Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study
title_short Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study
title_sort suture distension of schlemm's canal in canaloplasty: an anterior segment imaging study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452487/
https://www.ncbi.nlm.nih.gov/pubmed/26078874
http://dx.doi.org/10.1155/2015/457605
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