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Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study
Purpose. The object of this study was to investigate the role of the suture stent regarding its impact on reduction of intraocular pressure (IOP) in canaloplasty based on the distension of the inner wall of Schlemm's canal. Methods. Nineteen glaucoma patients who underwent canaloplasty with suc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452487/ https://www.ncbi.nlm.nih.gov/pubmed/26078874 http://dx.doi.org/10.1155/2015/457605 |
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author | Brandao, Livia M. Schötzau, Andreas Grieshaber, Matthias C. |
author_facet | Brandao, Livia M. Schötzau, Andreas Grieshaber, Matthias C. |
author_sort | Brandao, Livia M. |
collection | PubMed |
description | Purpose. The object of this study was to investigate the role of the suture stent regarding its impact on reduction of intraocular pressure (IOP) in canaloplasty based on the distension of the inner wall of Schlemm's canal. Methods. Nineteen glaucoma patients who underwent canaloplasty with successful positioning of the tensioning suture were included. The measurements were analyzed using linear mixed models, with the means adjusted to IOP, age, cup-to-disc ratio, and time of follow-up. Results. Mean follow-up time was 27.6 months (SD 10.5). Mean intraocular pressure (IOP) was 24.6 mmHg (SD 5.29), 13.8 (SD 2.65), and 14.5 (SD 0.71) before surgery, at 12 months, and at 36 months after surgery, respectively. 57.9% of patients had no medication at last evaluation. Differences and variations of measurements between the devices over a time of 12 months were not significant (p = 0.15 to 0.98). Some angles of distension associated with the suture stent inside SC were predictive for IOP reduction (p < 0.03 to < 0.001), but not for final IOP (p = 0.64 to 0.96). Conclusion. The angles of the inner wall of Schlemm's canal generated by the suture stent were comparable between OCT and UBM and did not change significantly over time. There was a tendency towards a greater distension of Schlemm's canal, when the difference was larger between pre- and postoperative IOP, suggesting the tensioning suture may contribute to IOP reduction. |
format | Online Article Text |
id | pubmed-4452487 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-44524872015-06-15 Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study Brandao, Livia M. Schötzau, Andreas Grieshaber, Matthias C. J Ophthalmol Research Article Purpose. The object of this study was to investigate the role of the suture stent regarding its impact on reduction of intraocular pressure (IOP) in canaloplasty based on the distension of the inner wall of Schlemm's canal. Methods. Nineteen glaucoma patients who underwent canaloplasty with successful positioning of the tensioning suture were included. The measurements were analyzed using linear mixed models, with the means adjusted to IOP, age, cup-to-disc ratio, and time of follow-up. Results. Mean follow-up time was 27.6 months (SD 10.5). Mean intraocular pressure (IOP) was 24.6 mmHg (SD 5.29), 13.8 (SD 2.65), and 14.5 (SD 0.71) before surgery, at 12 months, and at 36 months after surgery, respectively. 57.9% of patients had no medication at last evaluation. Differences and variations of measurements between the devices over a time of 12 months were not significant (p = 0.15 to 0.98). Some angles of distension associated with the suture stent inside SC were predictive for IOP reduction (p < 0.03 to < 0.001), but not for final IOP (p = 0.64 to 0.96). Conclusion. The angles of the inner wall of Schlemm's canal generated by the suture stent were comparable between OCT and UBM and did not change significantly over time. There was a tendency towards a greater distension of Schlemm's canal, when the difference was larger between pre- and postoperative IOP, suggesting the tensioning suture may contribute to IOP reduction. Hindawi Publishing Corporation 2015 2015-05-19 /pmc/articles/PMC4452487/ /pubmed/26078874 http://dx.doi.org/10.1155/2015/457605 Text en Copyright © 2015 Livia M. Brandao et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Brandao, Livia M. Schötzau, Andreas Grieshaber, Matthias C. Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study |
title | Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study |
title_full | Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study |
title_fullStr | Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study |
title_full_unstemmed | Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study |
title_short | Suture Distension of Schlemm's Canal in Canaloplasty: An Anterior Segment Imaging Study |
title_sort | suture distension of schlemm's canal in canaloplasty: an anterior segment imaging study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452487/ https://www.ncbi.nlm.nih.gov/pubmed/26078874 http://dx.doi.org/10.1155/2015/457605 |
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