UVB Stimulates the Expression of Endothelin B Receptor in Human Melanocytes via a Sequential Activation of the p38/MSK1/CREB/MITF Pathway Which Can Be Interrupted by a French Maritime Pine Bark Extract through a Direct Inactivation of MSK1

Melanogenesis is the physiological process by which melanin is synthesized to protect the skin from UV damage. While paracrine interactions between keratinocytes and melanocytes are crucial for regulating epidermal pigmentation, the endothelin (EDN)-endothelin B-receptor (EDNRB) interaction is one o...

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Detalles Bibliográficos
Autores principales: Tagashira, Hideki, Miyamoto, Aki, Kitamura, Sei-ichi, Tsubata, Masahito, Yamaguchi, Kazuya, Takagaki, Kinya, Imokawa, Genji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452497/
https://www.ncbi.nlm.nih.gov/pubmed/26030901
http://dx.doi.org/10.1371/journal.pone.0128678

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