Cargando…
Cumulative Risk, Cumulative Outcome: A 20-Year Longitudinal Study
Cumulative risk (CR) models provide some of the most robust findings in the developmental literature, predicting numerous and varied outcomes. Typically, however, these outcomes are predicted one at a time, across different samples, using concurrent designs, longitudinal designs of short duration, o...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452593/ https://www.ncbi.nlm.nih.gov/pubmed/26030616 http://dx.doi.org/10.1371/journal.pone.0127650 |
_version_ | 1782374322424250368 |
---|---|
author | Atkinson, Leslie Beitchman, Joseph Gonzalez, Andrea Young, Arlene Wilson, Beth Escobar, Michael Chisholm, Vivienne Brownlie, Elizabeth Khoury, Jennifer E. Ludmer, Jaclyn Villani, Vanessa |
author_facet | Atkinson, Leslie Beitchman, Joseph Gonzalez, Andrea Young, Arlene Wilson, Beth Escobar, Michael Chisholm, Vivienne Brownlie, Elizabeth Khoury, Jennifer E. Ludmer, Jaclyn Villani, Vanessa |
author_sort | Atkinson, Leslie |
collection | PubMed |
description | Cumulative risk (CR) models provide some of the most robust findings in the developmental literature, predicting numerous and varied outcomes. Typically, however, these outcomes are predicted one at a time, across different samples, using concurrent designs, longitudinal designs of short duration, or retrospective designs. We predicted that a single CR index, applied within a single sample, would prospectively predict diverse outcomes, i.e., depression, intelligence, school dropout, arrest, smoking, and physical disease from childhood to adulthood. Further, we predicted that number of risk factors would predict number of adverse outcomes (cumulative outcome; CO). We also predicted that early CR (assessed at age 5/6) explains variance in CO above and beyond that explained by subsequent risk (assessed at ages 12/13 and 19/20). The sample consisted of 284 individuals, 48% of whom were diagnosed with a speech/language disorder. Cumulative risk, assessed at 5/6-, 12/13-, and 19/20-years-old, predicted aforementioned outcomes at age 25/26 in every instance. Furthermore, number of risk factors was positively associated with number of negative outcomes. Finally, early risk accounted for variance beyond that explained by later risk in the prediction of CO. We discuss these findings in terms of five criteria posed by these data, positing a “mediated net of adversity” model, suggesting that CR may increase some central integrative factor, simultaneously augmenting risk across cognitive, quality of life, psychiatric and physical health outcomes. |
format | Online Article Text |
id | pubmed-4452593 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-44525932015-06-09 Cumulative Risk, Cumulative Outcome: A 20-Year Longitudinal Study Atkinson, Leslie Beitchman, Joseph Gonzalez, Andrea Young, Arlene Wilson, Beth Escobar, Michael Chisholm, Vivienne Brownlie, Elizabeth Khoury, Jennifer E. Ludmer, Jaclyn Villani, Vanessa PLoS One Research Article Cumulative risk (CR) models provide some of the most robust findings in the developmental literature, predicting numerous and varied outcomes. Typically, however, these outcomes are predicted one at a time, across different samples, using concurrent designs, longitudinal designs of short duration, or retrospective designs. We predicted that a single CR index, applied within a single sample, would prospectively predict diverse outcomes, i.e., depression, intelligence, school dropout, arrest, smoking, and physical disease from childhood to adulthood. Further, we predicted that number of risk factors would predict number of adverse outcomes (cumulative outcome; CO). We also predicted that early CR (assessed at age 5/6) explains variance in CO above and beyond that explained by subsequent risk (assessed at ages 12/13 and 19/20). The sample consisted of 284 individuals, 48% of whom were diagnosed with a speech/language disorder. Cumulative risk, assessed at 5/6-, 12/13-, and 19/20-years-old, predicted aforementioned outcomes at age 25/26 in every instance. Furthermore, number of risk factors was positively associated with number of negative outcomes. Finally, early risk accounted for variance beyond that explained by later risk in the prediction of CO. We discuss these findings in terms of five criteria posed by these data, positing a “mediated net of adversity” model, suggesting that CR may increase some central integrative factor, simultaneously augmenting risk across cognitive, quality of life, psychiatric and physical health outcomes. Public Library of Science 2015-06-01 /pmc/articles/PMC4452593/ /pubmed/26030616 http://dx.doi.org/10.1371/journal.pone.0127650 Text en © 2015 Atkinson et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Atkinson, Leslie Beitchman, Joseph Gonzalez, Andrea Young, Arlene Wilson, Beth Escobar, Michael Chisholm, Vivienne Brownlie, Elizabeth Khoury, Jennifer E. Ludmer, Jaclyn Villani, Vanessa Cumulative Risk, Cumulative Outcome: A 20-Year Longitudinal Study |
title | Cumulative Risk, Cumulative Outcome: A 20-Year Longitudinal Study |
title_full | Cumulative Risk, Cumulative Outcome: A 20-Year Longitudinal Study |
title_fullStr | Cumulative Risk, Cumulative Outcome: A 20-Year Longitudinal Study |
title_full_unstemmed | Cumulative Risk, Cumulative Outcome: A 20-Year Longitudinal Study |
title_short | Cumulative Risk, Cumulative Outcome: A 20-Year Longitudinal Study |
title_sort | cumulative risk, cumulative outcome: a 20-year longitudinal study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452593/ https://www.ncbi.nlm.nih.gov/pubmed/26030616 http://dx.doi.org/10.1371/journal.pone.0127650 |
work_keys_str_mv | AT atkinsonleslie cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT beitchmanjoseph cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT gonzalezandrea cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT youngarlene cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT wilsonbeth cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT escobarmichael cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT chisholmvivienne cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT brownlieelizabeth cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT khouryjennifere cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT ludmerjaclyn cumulativeriskcumulativeoutcomea20yearlongitudinalstudy AT villanivanessa cumulativeriskcumulativeoutcomea20yearlongitudinalstudy |