Identification of positron emission tomography (PET) tracer candidates by prediction of the target-bound fraction in the brain

BACKGROUND: Development of tracers for imaging with positron emission tomography (PET) is often a time-consuming process associated with considerable attrition. In an effort to simplify this process, we herein propose a mechanistically integrated approach for the selection of tracer candidates based...

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Detalles Bibliográficos
Autores principales: Fridén, Markus, Wennerberg, Marie, Antonsson, Madeleine, Sandberg-Ställ, Maria, Farde, Lars, Schou, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452637/
https://www.ncbi.nlm.nih.gov/pubmed/26116114
http://dx.doi.org/10.1186/s13550-014-0050-6

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