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Toxicity and radiation dosimetry studies of the serotonin transporter radioligand [(18) F]AFM in rats and monkeys

BACKGROUND: [(18) F]AFM is a potent and promising PET imaging agent for the serotonin transporter. We carried out an acute toxicity study in rats and radiation dosimetry in monkeys before the translation of the tracer to humans. METHODS: Single- and multiple-dose toxicity studies were conducted in S...

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Detalles Bibliográficos
Autores principales:	Huang, Ya-Yao, Cheng, Chen-Yi, Huang, Wen-Sheng, Ma, Kuo-Hsing, Tseng, Ta-Wei, Chou, Ta-Kai, Huang, Yiyun, Shiue, Chyng-Yann
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452647/ https://www.ncbi.nlm.nih.gov/pubmed/26116128 http://dx.doi.org/10.1186/s13550-014-0071-1

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