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Biliverdin reductase: a target for cancer therapy?

Biliverdin reductase (BVR) is a multifunctional protein that is the primary source of the potent antioxidant, bilirubin. BVR regulates activities/functions in the insulin/IGF-1/IRK/PI3K/MAPK pathways. Activation of certain kinases in these pathways is/are hallmark(s) of cancerous cells. The protein...

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Detalles Bibliográficos
Autores principales:	Gibbs, Peter E. M., Miralem, Tihomir, Maines, Mahin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452799/ https://www.ncbi.nlm.nih.gov/pubmed/26089799 http://dx.doi.org/10.3389/fphar.2015.00119

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