Genomic Context of Azole Resistance Mutations in Aspergillus fumigatus Determined Using Whole-Genome Sequencing

A rapid and global emergence of azole resistance has been observed in the pathogenic fungus Aspergillus fumigatus over the past decade. The dominant resistance mechanism appears to be of environmental origin and involves mutations in the cyp51A gene, which encodes a protein targeted by triazole anti...

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Detalles Bibliográficos
Autores principales: Abdolrasouli, Alireza, Rhodes, Johanna, Beale, Mathew A., Hagen, Ferry, Rogers, Thomas R., Chowdhary, Anuradha, Meis, Jacques F., Armstrong-James, Darius, Fisher, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453006/
https://www.ncbi.nlm.nih.gov/pubmed/26037120
http://dx.doi.org/10.1128/mBio.00536-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453006/
https://www.ncbi.nlm.nih.gov/pubmed/26037120
http://dx.doi.org/10.1128/mBio.00536-15

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