Fungal Inositol Pyrophosphate IP(7) Is Crucial for Metabolic Adaptation to the Host Environment and Pathogenicity

Inositol pyrophosphates (PP-IPs) comprising inositol, phosphate, and pyrophosphate (PP) are essential for multiple functions in eukaryotes. Their role in fungal pathogens has never been addressed. Cryptococcus neoformans is a model pathogenic fungus causing life-threatening meningoencephalitis. We i...

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Detalles Bibliográficos
Autores principales: Lev, Sophie, Li, Cecilia, Desmarini, Desmarini, Saiardi, Adolfo, Fewings, Nicole L., Schibeci, Stephen D., Sharma, Raghwa, Sorrell, Tania C., Djordjevic, Julianne T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453010/
https://www.ncbi.nlm.nih.gov/pubmed/26037119
http://dx.doi.org/10.1128/mBio.00531-15

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