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TIF1γ interferes with TGFβ1/SMAD4 signaling to promote poor outcome in operable breast cancer patients
BACKGROUND: The Transforming growth factor β (TGFβ) signaling has a paradoxical role in cancer development and outcome. Besides, the prognostic significance of the TGFβ1, SMAD4 in breast cancer patients is an area of many contradictions. The transcriptional intermediary factor 1γ (TIF1γ) is thought...
Autores principales: | Kassem, Loay, Deygas, Mathieu, Fattet, Laurent, Lopez, Jonathan, Goulvent, Thibaut, Lavergne, Emilie, Chabaud, Sylvie, Carrabin, Nicolas, Chopin, Nicolas, Bachelot, Thomas, Gillet, Germain, Treilleux, Isabelle, Rimokh, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453047/ https://www.ncbi.nlm.nih.gov/pubmed/26040677 http://dx.doi.org/10.1186/s12885-015-1471-y |
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