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Stent implantation of left main coronary artery stenosis in an infant: Effective long-term treatment?

Coronary artery stenosis is a rare phenomenon in children. Coronary stent implantation is generally not considered a standard treatment option due to technical difficulties and potential complications in this group of patients. Nevertheless, several pediatric cases reporting successful implantation...

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Autores principales: Paech, Christian, Dähnert, Ingo, Riede, Frank Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453186/
https://www.ncbi.nlm.nih.gov/pubmed/26085769
http://dx.doi.org/10.4103/0974-2069.157035
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author Paech, Christian
Dähnert, Ingo
Riede, Frank Thomas
author_facet Paech, Christian
Dähnert, Ingo
Riede, Frank Thomas
author_sort Paech, Christian
collection PubMed
description Coronary artery stenosis is a rare phenomenon in children. Coronary stent implantation is generally not considered a standard treatment option due to technical difficulties and potential complications in this group of patients. Nevertheless, several pediatric cases reporting successful implantation with acceptable short-term experiences have been described. The following case presents a successful stent implantation for left main coronary artery (LMCA) stenosis early after surgery for anomalous left coronary artery from pulmonary artery (ALCAPA) at the age of 6 months. The excellent mid-term results and notably the procedure's potential as a longterm treatment in small children are highlighted. A 6-month-old infant underwent surgery for ALCAPA. Due to sudden postoperative deterioration, cardiac catheterization was performed. Coronary angiography revealed severe (90%) ostial LMCA stenosis. A PROMUS drug-eluting stent (Promus Element AL3.0 × 8 mm, Boston Scientific, Natick, Massachusetts, USA) was implanted. The procedure was performed without complications. Antiplatelet therapy with acetylsalicylic acid and clopidogrel was initiated. Subsequently, cardiac function improved slowly. Cardiac catheterization 3 years 8 months after stent implantation showed no restenosis with a proximal LMCA diameter still at the 50(th) percentile for age. Neither were signs of heart failure reported at the last follow-up at 7 years of age. Presupposing normal growth, the implanted stent would thus provide sufficient myocardial perfusion with a LMCA lumen at the 40(th) percentile at the age of 16 years. In selected cases, coronary stent implantation may be an effective mid- to long-term treatment of coronary artery stenosis even in very young children.
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spelling pubmed-44531862015-06-17 Stent implantation of left main coronary artery stenosis in an infant: Effective long-term treatment? Paech, Christian Dähnert, Ingo Riede, Frank Thomas Ann Pediatr Cardiol Case Report Coronary artery stenosis is a rare phenomenon in children. Coronary stent implantation is generally not considered a standard treatment option due to technical difficulties and potential complications in this group of patients. Nevertheless, several pediatric cases reporting successful implantation with acceptable short-term experiences have been described. The following case presents a successful stent implantation for left main coronary artery (LMCA) stenosis early after surgery for anomalous left coronary artery from pulmonary artery (ALCAPA) at the age of 6 months. The excellent mid-term results and notably the procedure's potential as a longterm treatment in small children are highlighted. A 6-month-old infant underwent surgery for ALCAPA. Due to sudden postoperative deterioration, cardiac catheterization was performed. Coronary angiography revealed severe (90%) ostial LMCA stenosis. A PROMUS drug-eluting stent (Promus Element AL3.0 × 8 mm, Boston Scientific, Natick, Massachusetts, USA) was implanted. The procedure was performed without complications. Antiplatelet therapy with acetylsalicylic acid and clopidogrel was initiated. Subsequently, cardiac function improved slowly. Cardiac catheterization 3 years 8 months after stent implantation showed no restenosis with a proximal LMCA diameter still at the 50(th) percentile for age. Neither were signs of heart failure reported at the last follow-up at 7 years of age. Presupposing normal growth, the implanted stent would thus provide sufficient myocardial perfusion with a LMCA lumen at the 40(th) percentile at the age of 16 years. In selected cases, coronary stent implantation may be an effective mid- to long-term treatment of coronary artery stenosis even in very young children. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4453186/ /pubmed/26085769 http://dx.doi.org/10.4103/0974-2069.157035 Text en Copyright: © Annals of Pediatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Paech, Christian
Dähnert, Ingo
Riede, Frank Thomas
Stent implantation of left main coronary artery stenosis in an infant: Effective long-term treatment?
title Stent implantation of left main coronary artery stenosis in an infant: Effective long-term treatment?
title_full Stent implantation of left main coronary artery stenosis in an infant: Effective long-term treatment?
title_fullStr Stent implantation of left main coronary artery stenosis in an infant: Effective long-term treatment?
title_full_unstemmed Stent implantation of left main coronary artery stenosis in an infant: Effective long-term treatment?
title_short Stent implantation of left main coronary artery stenosis in an infant: Effective long-term treatment?
title_sort stent implantation of left main coronary artery stenosis in an infant: effective long-term treatment?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453186/
https://www.ncbi.nlm.nih.gov/pubmed/26085769
http://dx.doi.org/10.4103/0974-2069.157035
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