Microvascular obstruction and endothelial activation are independently associated with the clinical manifestations of severe falciparum malaria in adults: an observational study

BACKGROUND: Microvascular obstruction and endothelial dysfunction have both been linked to tissue hypoperfusion in falciparum malaria, but their relative contributions to the disease’s pathogenesis and outcome are unknown. METHODS: Microvascular blood flow was quantified in adults with severe falcip...

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Detalles Bibliográficos
Autores principales: Hanson, Josh, Lee, Sue J., Hossain, Md Amir, Anstey, Nicholas M., Charunwatthana, Prakaykaew, Maude, Richard J., Kingston, Hugh W. F., Mishra, Saroj K., Mohanty, Sanjib, Plewes, Katherine, Piera, Kim, Hassan, Mahtab U., Ghose, Aniruddha, Faiz, M. Abul, White, Nicholas J., Day, Nicholas P. J., Dondorp, Arjen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453275/
https://www.ncbi.nlm.nih.gov/pubmed/26018532
http://dx.doi.org/10.1186/s12916-015-0365-9

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