The Fungal Quorum-Sensing Molecule Farnesol Activates Innate Immune Cells but Suppresses Cellular Adaptive Immunity

Farnesol, produced by the polymorphic fungus Candida albicans, is the first quorum-sensing molecule discovered in eukaryotes. Its main function is control of C. albicans filamentation, a process closely linked to pathogenesis. In this study, we analyzed the effects of farnesol on innate immune cells...

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Detalles Bibliográficos
Autores principales: Leonhardt, Ines, Spielberg, Steffi, Weber, Michael, Albrecht-Eckardt, Daniela, Bläss, Markus, Claus, Ralf, Barz, Dagmar, Scherlach, Kirstin, Hertweck, Christian, Löffler, Jürgen, Hünniger, Kerstin, Kurzai, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453522/
https://www.ncbi.nlm.nih.gov/pubmed/25784697
http://dx.doi.org/10.1128/mBio.00143-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453522/
https://www.ncbi.nlm.nih.gov/pubmed/25784697
http://dx.doi.org/10.1128/mBio.00143-15

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