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A Modified R-Type Bacteriocin Specifically Targeting Clostridium difficile Prevents Colonization of Mice without Affecting Gut Microbiota Diversity
Clostridium difficile is a leading cause of nosocomial infections worldwide and has become an urgent public health threat requiring immediate attention. Epidemic lineages of the BI/NAP1/027 strain type have emerged and spread through health care systems across the globe over the past decade. Limitin...
Autores principales: | Gebhart, Dana, Lok, Stephen, Clare, Simon, Tomas, Myreen, Stares, Mark, Scholl, Dean, Donskey, Curtis J., Lawley, Trevor D., Govoni, Gregory R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453579/ https://www.ncbi.nlm.nih.gov/pubmed/25805733 http://dx.doi.org/10.1128/mBio.02368-14 |
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