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Prognostic and predictive values of EGFR overexpression and EGFR copy number alteration in HER2-positive breast cancer
BACKGROUND: Epidermal growth factor receptor (EGFR) is overexpressed in a subset of human epidermal growth factor receptor 2 (HER2)-positive breast cancers, and coexpression of HER2 and EGFR has been reported to be associated with poor clinical outcome. Moreover, interaction between HER2 and EGFR ha...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453607/ https://www.ncbi.nlm.nih.gov/pubmed/25349977 http://dx.doi.org/10.1038/bjc.2014.556 |