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Comprehensive validation of published immunohistochemical prognostic biomarkers of prostate cancer—what has gone wrong? A blueprint for the way forward in biomarker studies

BACKGROUND: Treatment planning of localised prostate cancer remains challenging. Besides conventional parameters, a wealth of prognostic biomarkers has been proposed so far. None of which, however, have successfully been implemented in a routine setting so far. The aim of our study was to systematic...

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Detalles Bibliográficos
Autores principales: Huber, F, Montani, M, Sulser, T, Jaggi, R, Wild, P, Moch, H, Gevensleben, H, Schmid, M, Wyder, S, Kristiansen, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453620/
https://www.ncbi.nlm.nih.gov/pubmed/25422912
http://dx.doi.org/10.1038/bjc.2014.588