Stress hormones reduce the efficacy of paclitaxel in triple negative breast cancer through induction of DNA damage

BACKGROUND: The mechanisms by which stress hormones impact triple-negative breast cancer (TNBC) etiology and treatment are unclear. We have previously shown that stress hormones, cortisol, and catecholamines induce rapid DNA damage and impact DNA repair in NIH 3T3 fibroblasts. This study investigate...

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Detalles Bibliográficos
Autores principales: Reeder, A, Attar, M, Nazario, L, Bathula, C, Zhang, A, Hochbaum, D, Roy, E, Cooper, K L, Oesterreich, S, Davidson, N E, Neumann, C A, Flint, M S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453678/
https://www.ncbi.nlm.nih.gov/pubmed/25880007
http://dx.doi.org/10.1038/bjc.2015.133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453678/
https://www.ncbi.nlm.nih.gov/pubmed/25880007
http://dx.doi.org/10.1038/bjc.2015.133

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