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Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation

BACKGROUND: Despite its promise as a highly useful therapy for pancreatic cancer (PC), the addition of external beam radiation therapy to PC treatment has shown varying success in clinical trials. Understanding PC radioresistance and discovery of methods to sensitise PC to radiation will increase pa...

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Detalles Bibliográficos
Autores principales:	Souchek, J J, Baine, M J, Lin, C, Rachagani, S, Gupta, S, Kaur, S, Lester, K, Zheng, D, Chen, S, Smith, L, Lazenby, A, Johansson, S L, Jain, M, Batra, S K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453840/ https://www.ncbi.nlm.nih.gov/pubmed/25025965 http://dx.doi.org/10.1038/bjc.2014.385

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