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Aptamer-based Sandwich Assay and its Clinical Outlooks for Detecting Lipocalin-2 in Hepatocellular Carcinoma (HCC)

We validated a single-stranded, DNA aptamer-based, diagnostic method capable of detecting Lipocalin-2 (LCN2), a biomarker from clinically relevant hepatocellular carcinoma (HCC) patient serum, in the sandwich assay format. Nine aptamers (LCN2_apta1 to LCN2_apta9) for LCN2 were screened with SELEX pr...

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Detalles Bibliográficos
Autores principales:	Lee, Kyeong-Ah, Ahn, Ji-Young, Lee, Sang-Hee, Singh Sekhon, Simranjeet, Kim, Dae-Ghon, Min, Jiho, Kim, Yang-Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454046/ https://www.ncbi.nlm.nih.gov/pubmed/26039737 http://dx.doi.org/10.1038/srep10897

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