Primary Splenic Angiosarcoma Revealed by Bone Marrow Metastasis

Primary splenic angiosarcomas are the most common malignant non-hematopoietic tumors of the spleen. Metastatic diseases were found in 69% of patients in a reported series but the incidence of bone marrow involvement is unclear. We report a rare case of a 25-years-old Moroccan woman with unsuspected...

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Detalles Bibliográficos
Autores principales: Anoun, Soumaya, Marouane, Sofia, Quessar, Asmae, Benchekroun, Said
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454058/
https://www.ncbi.nlm.nih.gov/pubmed/25541659
http://dx.doi.org/10.4274/tjh.2013.0049
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author Anoun, Soumaya
Marouane, Sofia
Quessar, Asmae
Benchekroun, Said
author_facet Anoun, Soumaya
Marouane, Sofia
Quessar, Asmae
Benchekroun, Said
author_sort Anoun, Soumaya
collection PubMed
description Primary splenic angiosarcomas are the most common malignant non-hematopoietic tumors of the spleen. Metastatic diseases were found in 69% of patients in a reported series but the incidence of bone marrow involvement is unclear. We report a rare case of a 25-years-old Moroccan woman with unsuspected primary splenic angiosarcoma revealed by bone marrow metastasis. She presented with serious anemia and splenomegaly. Bone marrow biopsy revealed proliferating spindle cells. Computed tomography scanning showed an enlarged spleen with heterogeneous lesions. Splenectomy was performed and retrospective histological study of the spleen confirmed the diagnosis. She died 1 year after splenectomy.
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spelling pubmed-44540582016-01-12 Primary Splenic Angiosarcoma Revealed by Bone Marrow Metastasis Anoun, Soumaya Marouane, Sofia Quessar, Asmae Benchekroun, Said Turk J Haematol Case Report Primary splenic angiosarcomas are the most common malignant non-hematopoietic tumors of the spleen. Metastatic diseases were found in 69% of patients in a reported series but the incidence of bone marrow involvement is unclear. We report a rare case of a 25-years-old Moroccan woman with unsuspected primary splenic angiosarcoma revealed by bone marrow metastasis. She presented with serious anemia and splenomegaly. Bone marrow biopsy revealed proliferating spindle cells. Computed tomography scanning showed an enlarged spleen with heterogeneous lesions. Splenectomy was performed and retrospective histological study of the spleen confirmed the diagnosis. She died 1 year after splenectomy. Galenos Publishing 2014-12 2014-12-05 /pmc/articles/PMC4454058/ /pubmed/25541659 http://dx.doi.org/10.4274/tjh.2013.0049 Text en © Turkish Journal of Hematology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Anoun, Soumaya
Marouane, Sofia
Quessar, Asmae
Benchekroun, Said
Primary Splenic Angiosarcoma Revealed by Bone Marrow Metastasis
title Primary Splenic Angiosarcoma Revealed by Bone Marrow Metastasis
title_full Primary Splenic Angiosarcoma Revealed by Bone Marrow Metastasis
title_fullStr Primary Splenic Angiosarcoma Revealed by Bone Marrow Metastasis
title_full_unstemmed Primary Splenic Angiosarcoma Revealed by Bone Marrow Metastasis
title_short Primary Splenic Angiosarcoma Revealed by Bone Marrow Metastasis
title_sort primary splenic angiosarcoma revealed by bone marrow metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454058/
https://www.ncbi.nlm.nih.gov/pubmed/25541659
http://dx.doi.org/10.4274/tjh.2013.0049
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AT benchekrounsaid primarysplenicangiosarcomarevealedbybonemarrowmetastasis

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