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Comparison of energy metabolism and nutritional status of hospitalized patients with Crohn’s disease and those with ulcerative colitis

This study aimed to compare the nutritional status and energy expenditure of hospitalized patients with Crohn’s disease (CD) and those with ulcerative colitis (UC). Twenty-two hospitalized patients with CD and 18 patients with UC were enrolled in this study. We analyzed nutritional status upon admis...

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Autores principales: Takaoka, Azusa, Sasaki, Masaya, Kurihara, Mika, Iwakawa, Hiromi, Inoue, Mai, Bamba, Shigeki, Ban, Hiromitsu, Andoh, Akira, Miyazaki, Yoshiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454083/
https://www.ncbi.nlm.nih.gov/pubmed/26060351
http://dx.doi.org/10.3164/jcbn.14-95
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author Takaoka, Azusa
Sasaki, Masaya
Kurihara, Mika
Iwakawa, Hiromi
Inoue, Mai
Bamba, Shigeki
Ban, Hiromitsu
Andoh, Akira
Miyazaki, Yoshiko
author_facet Takaoka, Azusa
Sasaki, Masaya
Kurihara, Mika
Iwakawa, Hiromi
Inoue, Mai
Bamba, Shigeki
Ban, Hiromitsu
Andoh, Akira
Miyazaki, Yoshiko
author_sort Takaoka, Azusa
collection PubMed
description This study aimed to compare the nutritional status and energy expenditure of hospitalized patients with Crohn’s disease (CD) and those with ulcerative colitis (UC). Twenty-two hospitalized patients with CD and 18 patients with UC were enrolled in this study. We analyzed nutritional status upon admission by using nutritional screening tools including subjective global assessment, malnutrition universal screening tool, and laboratory tests. We measured resting energy expenditure (mREE) of the patients with indirect calorimetry and predicted resting energy expenditure (pREE) was calculated by using the Harris-Benedict equation. Results presented here indicate no significant difference in nutritional parameters and energy metabolism between CD and UC patients. In UC patients, a significant correlation was observed between mREE/body weight and disease activity detected by the Lichtiger and Seo indices. However, there was no correlation between mREE/body weight and Crohn’s disease activity index in CD patients. Inflammatory cytokine interleukin-6 levels correlated with mREE/pREE in CD and UC patients while tumor necrosis factor-α was not. In conclusion, energy expenditure significantly correlated with disease activity in UC patients but not in CD patients. These results indicate that establishing daily energy requirements based on disease activity of UC is imperative for improving the nutritional status of patients.
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spelling pubmed-44540832015-07-01 Comparison of energy metabolism and nutritional status of hospitalized patients with Crohn’s disease and those with ulcerative colitis Takaoka, Azusa Sasaki, Masaya Kurihara, Mika Iwakawa, Hiromi Inoue, Mai Bamba, Shigeki Ban, Hiromitsu Andoh, Akira Miyazaki, Yoshiko J Clin Biochem Nutr Original Article This study aimed to compare the nutritional status and energy expenditure of hospitalized patients with Crohn’s disease (CD) and those with ulcerative colitis (UC). Twenty-two hospitalized patients with CD and 18 patients with UC were enrolled in this study. We analyzed nutritional status upon admission by using nutritional screening tools including subjective global assessment, malnutrition universal screening tool, and laboratory tests. We measured resting energy expenditure (mREE) of the patients with indirect calorimetry and predicted resting energy expenditure (pREE) was calculated by using the Harris-Benedict equation. Results presented here indicate no significant difference in nutritional parameters and energy metabolism between CD and UC patients. In UC patients, a significant correlation was observed between mREE/body weight and disease activity detected by the Lichtiger and Seo indices. However, there was no correlation between mREE/body weight and Crohn’s disease activity index in CD patients. Inflammatory cytokine interleukin-6 levels correlated with mREE/pREE in CD and UC patients while tumor necrosis factor-α was not. In conclusion, energy expenditure significantly correlated with disease activity in UC patients but not in CD patients. These results indicate that establishing daily energy requirements based on disease activity of UC is imperative for improving the nutritional status of patients. the Society for Free Radical Research Japan 2015-05 2015-04-16 /pmc/articles/PMC4454083/ /pubmed/26060351 http://dx.doi.org/10.3164/jcbn.14-95 Text en Copyright © 2015 JCBN This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Takaoka, Azusa
Sasaki, Masaya
Kurihara, Mika
Iwakawa, Hiromi
Inoue, Mai
Bamba, Shigeki
Ban, Hiromitsu
Andoh, Akira
Miyazaki, Yoshiko
Comparison of energy metabolism and nutritional status of hospitalized patients with Crohn’s disease and those with ulcerative colitis
title Comparison of energy metabolism and nutritional status of hospitalized patients with Crohn’s disease and those with ulcerative colitis
title_full Comparison of energy metabolism and nutritional status of hospitalized patients with Crohn’s disease and those with ulcerative colitis
title_fullStr Comparison of energy metabolism and nutritional status of hospitalized patients with Crohn’s disease and those with ulcerative colitis
title_full_unstemmed Comparison of energy metabolism and nutritional status of hospitalized patients with Crohn’s disease and those with ulcerative colitis
title_short Comparison of energy metabolism and nutritional status of hospitalized patients with Crohn’s disease and those with ulcerative colitis
title_sort comparison of energy metabolism and nutritional status of hospitalized patients with crohn’s disease and those with ulcerative colitis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454083/
https://www.ncbi.nlm.nih.gov/pubmed/26060351
http://dx.doi.org/10.3164/jcbn.14-95
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