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CD38-mediated Ca(2+) signaling contributes to glucagon-induced hepatic gluconeogenesis
CD38 is a multifunctional enzyme for the synthesis of Ca(2+) second messengers. Glucagon promotes hepatic glucose production through Ca(2+) signaling in the fasting condition. In this study, we investigated the role of CD38 in the glucagon signaling of hepatocytes. Here, we show that glucagon induce...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454144/ https://www.ncbi.nlm.nih.gov/pubmed/26038839 http://dx.doi.org/10.1038/srep10741 |