Cargando…
CD38-mediated Ca(2+) signaling contributes to glucagon-induced hepatic gluconeogenesis
CD38 is a multifunctional enzyme for the synthesis of Ca(2+) second messengers. Glucagon promotes hepatic glucose production through Ca(2+) signaling in the fasting condition. In this study, we investigated the role of CD38 in the glucagon signaling of hepatocytes. Here, we show that glucagon induce...
Autores principales: | Rah, So-Young, Kim, Uh-Hyun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454144/ https://www.ncbi.nlm.nih.gov/pubmed/26038839 http://dx.doi.org/10.1038/srep10741 |
Ejemplares similares
-
CD38/ADP-ribose/TRPM2-mediated nuclear Ca(2+) signaling is essential for hepatic gluconeogenesis in fasting and diabetes
por: Rah, So-Young, et al.
Publicado: (2023) -
NAADP-mediated Ca(2+) signaling promotes autophagy and protects against LPS-induced liver injury
por: Rah, So-Young, et al.
Publicado: (2017) -
Glucagon stimulates gluconeogenesis by InsP(3)R-I mediated hepatic lipolysis
por: Perry, Rachel J., et al.
Publicado: (2020) -
Neuronal regulation of glucagon secretion and gluconeogenesis
por: Thorens, Bernard
Publicado: (2022) -
Glucagon changes substrate preference in gluconeogenesis
por: Xu, Huiting, et al.
Publicado: (2022)