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Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells

Depletion of arginine by recombinant human arginase (rhArg) has proven to be an effective cancer therapeutic approach for a variety of malignant tumors. Triple-negative breast cancers (TNBCs) lack of specific therapeutic targets, resulting in poor prognosis and limited therapeutic efficacy. To explo...

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Detalles Bibliográficos
Autores principales: Wang, Z, Shi, X, Li, Y, Fan, J, Zeng, X, Xian, Z, Sun, Y, Wang, S, Song, P, Zhao, S, Hu, H, Ju, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454157/
https://www.ncbi.nlm.nih.gov/pubmed/25501824
http://dx.doi.org/10.1038/cddis.2014.503