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Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia

The activation of microglia, resident immune cells of the central nervous system, and inflammation-mediated neurotoxicity are typical features of neurodegenerative diseases, for example, Alzheimer's and Parkinson's diseases. An unexpected role of caspase-3, commonly known to have execution...

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Detalles Bibliográficos
Autores principales:	Kavanagh, E, Rodhe, J, Burguillos, M A, Venero, J L, Joseph, B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454160/ https://www.ncbi.nlm.nih.gov/pubmed/25501826 http://dx.doi.org/10.1038/cddis.2014.514

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