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Defective sarcoplasmic reticulum–mitochondria calcium exchange in aged mouse myocardium
Mitochondrial alterations are critically involved in increased vulnerability to disease during aging. We investigated the contribution of mitochondria–sarcoplasmic reticulum (SR) communication in cardiomyocyte functional alterations during aging. Heart function (echocardiography) and ATP/phosphocrea...
Autores principales: | Fernandez-Sanz, C, Ruiz-Meana, M, Miro-Casas, E, Nuñez, E, Castellano, J, Loureiro, M, Barba, I, Poncelas, M, Rodriguez-Sinovas, A, Vázquez, J, Garcia-Dorado, D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454162/ https://www.ncbi.nlm.nih.gov/pubmed/25522267 http://dx.doi.org/10.1038/cddis.2014.526 |
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