Cargando…

Heme oxygenase-1 protects against Alzheimer's amyloid-β(1-42)-induced toxicity via carbon monoxide production

Heme oxygenase-1 (HO-1), an inducible enzyme up-regulated in Alzheimer's disease, catabolises heme to biliverdin, Fe(2+) and carbon monoxide (CO). CO can protect neurones from oxidative stress-induced apoptosis by inhibiting Kv2.1 channels, which mediates cellular K(+) efflux as an early step i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hettiarachchi, N, Dallas, M, Al-Owais, M, Griffiths, H, Hooper, N, Scragg, J, Boyle, J, Peers, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454163/ https://www.ncbi.nlm.nih.gov/pubmed/25501830 http://dx.doi.org/10.1038/cddis.2014.529

Ejemplares similares

Heme oxygenase-1 derived carbon monoxide suppresses Aβ(1–42) toxicity in astrocytes
por: Hettiarachchi, Nishani T, et al.
Publicado: (2017)

Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca(2+) channels
por: Duckles, Hayley, et al.
Publicado: (2014)

Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K(+) channel Kv1.5
por: Al-Owais, Moza M, et al.
Publicado: (2017)

Beneficial effects of the heme oxygenase-1/carbon monoxide system
por: Takeyama, N, et al.
Publicado: (2009)

Heme oxygenase-1 and carbon monoxide in pulmonary medicine
por: Slebos, Dirk-Jan, et al.
Publicado: (2003)

Inhibition of the Cardiac Na(+) Channel Nav1.5 by Carbon Monoxide
por: Elies, Jacobo, et al.
Publicado: (2014)

A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K(+) channels in carbon monoxide–induced proarrhythmic early afterdepolarizations
por: Al-Owais, Moza M., et al.
Publicado: (2017)

The role of carbon monoxide and heme oxygenase-1 in COVID-19
por: Kwong, Kenneth K., et al.
Publicado: (2020)

Therapeutic Potential of Heme Oxygenase-1/Carbon Monoxide in Lung Disease
por: Constantin, Myrna, et al.
Publicado: (2012)

Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2.1
por: Dallas, Mark L., et al.
Publicado: (2021)

Carbon Monoxide Generated by Heme Oxygenase 1 Suppresses Endothelial Cell Apoptosis
por: Brouard, Sophie, et al.
Publicado: (2000)

Heme oxygenase-1 derived carbon monoxide permits maturation of myeloid cells
por: Wegiel, B, et al.
Publicado: (2014)

Heme oxygenase and carbon monoxide protect from muscle dystrophy
por: Chan, Mun Chun, et al.
Publicado: (2016)

Aging and Progression of Beta-Amyloid Pathology in Alzheimer’s Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression
por: Fernández-Mendívil, Cristina, et al.
Publicado: (2020)

Amyloid Beta-Mediated Hypomethylation of Heme Oxygenase 1 Correlates with Cognitive Impairment in Alzheimer’s Disease
por: Sung, Hye Youn, et al.
Publicado: (2016)

Adaptive Potential of the Heme Oxygenase/Carbon Monoxide Pathway During Hypoxia
por: Tift, Michael S., et al.
Publicado: (2020)

Heme oxygenase/carbon monoxide signaling pathways: Regulation and functional significance
por: Ryter, Stefan W., et al.
Publicado: (2002)

Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1–dependent pathway
por: Hegazi, Refaat A.F., et al.
Publicado: (2005)

Application of Heme Oxygenase-1, Carbon Monoxide and Biliverdin for the Prevention of Intestinal Ischemia/Reperfusion Injury
por: Nakao, Atsunori, et al.
Publicado: (2008)

Carbon Monoxide (CO) as a Retinal Regulator of Heme Oxygenases -1, and -2 (HO’s) Expression
por: Nowak, Sławomir, et al.
Publicado: (2022)

Carbon Monoxide Protects against Liver Failure through Nitric Oxide–induced Heme Oxygenase 1
por: Zuckerbraun, Brian S., et al.
Publicado: (2003)

Inhibition of the voltage-gated potassium channel Kv1.5 by hydrogen sulfide attenuates remodeling through S-nitrosylation-mediated signaling
por: Al-Owais, Moza M., et al.
Publicado: (2023)

Heme Oxygenase-1 Deficiency
por: Renji, Soumya, et al.
Publicado: (2021)

Introduction to Serial Review: Heme Oxygenase and Carbon Monoxide: Medicinal Chemistry and Biological Effects
por: Naito, Yuji
Publicado: (2008)

Effect of heme oxygenase–endogenous carbon monoxide on mortality during septic shock in rats
por: Yu, J.-b., et al.
Publicado: (2008)

Heme Oxygenase-1 Induction by Carbon Monoxide Releasing Molecule-3 Suppresses Interleukin-1β-Mediated Neuroinflammation
por: Lin, Chih-Chung, et al.
Publicado: (2017)

Carbon Monoxide Induces Heme Oxygenase-1 to Modulate STAT3 Activation in Endothelial Cells via S-Glutathionylation
por: Yang, Yan-Chang, et al.
Publicado: (2014)

Therapeutic Potential of Heme Oxygenase-1 and Carbon Monoxide in Acute Organ Injury, Critical Illness, and Inflammatory Disorders
por: Ryter, Stefan W.
Publicado: (2020)

IRG1 induced by heme oxygenase-1/carbon monoxide inhibits LPS-mediated sepsis and pro-inflammatory cytokine production
por: Jamal Uddin, Md, et al.
Publicado: (2016)

Heme oxygenase 1 regulates osteoclastogenesis
por: Zwerina, J, et al.
Publicado: (2005)

Carbon Monoxide Regulates Macrophage Differentiation and Polarization toward the M2 Phenotype through Upregulation of Heme Oxygenase 1
por: Kang, In-Soon, et al.
Publicado: (2021)

The Diverse Roles of Heme Oxygenase-1 in Tumor Progression
por: Luu Hoang, Kim Ngan, et al.
Publicado: (2021)

Therapeutic Roles of Heme Oxygenase-1 in Metabolic Diseases: Curcumin and Resveratrol Analogues as Possible Inducers of Heme Oxygenase-1
por: Son, Yong, et al.
Publicado: (2013)

Activation of locus coeruleus heme oxygenase-carbon monoxide pathway promoted an anxiolytic-like effect in rats
por: Carvalho-Costa, P.G., et al.
Publicado: (2016)

Upregulation of heme oxygenase-1 in colorectal cancer patients with increased circulation carbon monoxide levels, potentially affects chemotherapeutic sensitivity
por: Yin, Hongzhuan, et al.
Publicado: (2014)

The protective role of localized nitric oxide production during inflammation may be mediated by the heme oxygenase-1/carbon monoxide pathway
por: Iwata, Masahiro, et al.
Publicado: (2020)

Therapeutic Potential of Heme Oxygenase-1 in Aneurysmal Diseases
por: Jiang, Wei-Cheng, et al.
Publicado: (2020)

Integrative Survival Response Evoked by Heme Oxygenase-1 and Heme Metabolites
por: Pae, Hyun-Ock, et al.
Publicado: (2008)

How Heme Oxygenase-1 Prevents Heme-Induced Cell Death
por: Lanceta, Lilibeth, et al.
Publicado: (2015)

Heme, Heme Oxygenase-1, Statins, and SARS-CoV-2
por: Stevenson, David K., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kr09tehaifvtabdfurr7l99e7h