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Cell shape impacts on the positioning of the mitotic spindle with respect to the substratum

All known mechanisms of mitotic spindle orientation rely on astral microtubules. We report that even in the absence of astral microtubules, metaphase spindles in MDCK and HeLa cells are not randomly positioned along their x-z dimension, but preferentially adopt shallow β angles between spindle pole...

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Detalles Bibliográficos
Autores principales:	Lázaro-Diéguez, Francisco, Ispolatov, Iaroslav, Müsch, Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454176/ https://www.ncbi.nlm.nih.gov/pubmed/25657320 http://dx.doi.org/10.1091/mbc.E14-08-1330

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