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Size-dependent leak of soluble and membrane proteins through the yeast nuclear pore complex

Nuclear pore complexes (NPCs) allow selective import and export while forming a barrier for untargeted proteins. Using fluorescence microscopy, we measured in vivo the permeability of the Saccharomyces cerevisiae NPC for multidomain proteins of different sizes and found that soluble proteins of 150...

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Detalles Bibliográficos
Autores principales:	Popken, Petra, Ghavami, Ali, Onck, Patrick R., Poolman, Bert, Veenhoff, Liesbeth M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454183/ https://www.ncbi.nlm.nih.gov/pubmed/25631821 http://dx.doi.org/10.1091/mbc.E14-07-1175

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