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Itraconazole solid dispersion prepared by a supercritical fluid technique: preparation, in vitro characterization, and bioavailability in beagle dogs

This research aimed to develop a supercritical fluid (SCF) technique for preparing a particulate form of itraconazole (ITZ) with good dissolution and bioavailability characteristics. The ITZ particulate solid dispersion was formulated with hydroxypropyl methylcellulose, Pluronic F-127, and L-ascorbi...

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Detalles Bibliográficos
Autores principales:	Yin, Xuezhi, Daintree, Linda Sharon, Ding, Sheng, Ledger, Daniel Mark, Wang, Bing, Zhao, Wenwen, Qi, Jianping, Wu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454206/ https://www.ncbi.nlm.nih.gov/pubmed/26060397 http://dx.doi.org/10.2147/DDDT.S81253

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