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Population pharmacokinetics of methylphenidate hydrochloride extended-release multiple-layer beads in pediatric subjects with attention deficit hyperactivity disorder
A new multilayer-bead formulation of extended-release methylphenidate hydrochloride (MPH-MLR) has been evaluated in pharmacokinetic studies in healthy adults and in Phase III efficacy/safety studies in children and adolescents with attention deficit hyperactivity disorder (ADHD). Using available dat...
Autores principales: | Teuscher, Nathan S, Adjei, Akwete, Findling, Robert L, Greenhill, Laurence L, Kupper, Robert J, Wigal, Sharon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454220/ https://www.ncbi.nlm.nih.gov/pubmed/26060393 http://dx.doi.org/10.2147/DDDT.S83234 |
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