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Depletion of intermediate filament protein Nestin, a target of microRNA-940, suppresses tumorigenesis by inducing spontaneous DNA damage accumulation in human nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is a major malignant tumor of the head and neck region in southern China. The understanding of its underlying etiology is essential for the development of novel effective therapies. We report for the first time that microRNA-940 (miR-940) significantly suppresses the p...

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Detalles Bibliográficos
Autores principales: Ma, J, Sun, F, Li, C, Zhang, Y, Xiao, W, Li, Z, Pan, Q, Zeng, H, Xiao, G, Yao, K, Hong, A, An, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454294/
https://www.ncbi.nlm.nih.gov/pubmed/25118937
http://dx.doi.org/10.1038/cddis.2014.293