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Release and activity of histone in diseases

Histones and their post-translational modifications have key roles in chromatin remodeling and gene transcription. Besides intranuclear functions, histones act as damage-associated molecular pattern molecules when they are released into the extracellular space. Administration of exogenous histones t...

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Detalles Bibliográficos
Autores principales: Chen, R, Kang, R, Fan, X-G, Tang, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454312/
https://www.ncbi.nlm.nih.gov/pubmed/25118930
http://dx.doi.org/10.1038/cddis.2014.337