The RING ubiquitin E3 RNF114 interacts with A20 and modulates NF-κB activity and T-cell activation

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Accurate regulation of nuclear factor-κB (NF-κB) activity is crucial to prevent a variety of disorders including immune and inflammatory diseases. Active NF-κB promotes IκBα and A20 expression, important negative regulatory molecules that control the NF-κB response. In this study, using two-hybrid s...

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Detalles Bibliográficos
Autores principales: Rodriguez, M S, Egaña, I, Lopitz-Otsoa, F, Aillet, F, Lopez-Mato, M P, Dorronroso, A, Lobato-Gil, S, Sutherland, J D, Barrio, R, Trigueros, C, Lang, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454333/
https://www.ncbi.nlm.nih.gov/pubmed/25165885
http://dx.doi.org/10.1038/cddis.2014.366
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