Arsenic Trioxide Sensitizes Glioblastoma to a Myc Inhibitor

Glioblastoma multiforme (GBM) is associated with high mortality due to infiltrative growth and recurrence. Median survival of the patients is less than 15 months, increasing requirements for new therapies. We found that both arsenic trioxide and 10058F4, an inhibitor of Myc, induced differentiation...

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Detalles Bibliográficos
Autores principales: Yoshimura, Yayoi, Shiino, Akihiko, Muraki, Kazue, Fukami, Tadateru, Yamada, Shigeki, Satow, Takeshi, Fukuda, Miyuki, Saiki, Masaaki, Hojo, Masato, Miyamoto, Susumu, Onishi, Nobuyuki, Saya, Hideyuki, Inubushi, Toshiro, Nozaki, Kazuhiko, Tanigaki, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454553/
https://www.ncbi.nlm.nih.gov/pubmed/26038891
http://dx.doi.org/10.1371/journal.pone.0128288

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