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Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation

Allergic asthma is a chronic, inflammatory lung disease. Some forms of allergic asthma are characterized by Th2-driven eosinophilia while others are distinguished by Th17-driven neutrophilia. Stimulation of Toll-like receptor 4 (TLR4) on hematopoietic and airway epithelial cells (AECs) contributes t...

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Detalles Bibliográficos
Autores principales: McAlees, Jaclyn W., Whitehead, Gregory S., Harley, Isaac T.W., Cappelletti, Monica, Rewerts, Cheryl L., Holdcroft, A. Maria, Divanovic, Senad, Wills-Karp, Marsha, Finkelman, Fred D., Karp, Christopher L., Cook, Donald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454628/
https://www.ncbi.nlm.nih.gov/pubmed/25465099
http://dx.doi.org/10.1038/mi.2014.117