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Design and Evaluation of Antimalarial Peptides Derived from Prediction of Short Linear Motifs in Proteins Related to Erythrocyte Invasion

The purpose of this study was to investigate the blood stage of the malaria causing parasite, Plasmodium falciparum, to predict potential protein interactions between the parasite merozoite and the host erythrocyte and design peptides that could interrupt these predicted interactions. We screened th...

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Detalles Bibliográficos
Autores principales: Bianchin, Alessandra, Bell, Angus, Chubb, Anthony J., Doolan, Nathalie, Leneghan, Darren, Stavropoulos, Ilias, Shields, Denis C., Mooney, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454681/
https://www.ncbi.nlm.nih.gov/pubmed/26039561
http://dx.doi.org/10.1371/journal.pone.0127383