CF750-A33scFv-Fc-Based Optical Imaging of Subcutaneous and Orthotopic Xenografts of GPA33-Positive Colorectal Cancer in Mice

Antibody-based imaging agents are attractive as adjuvant diagnostic tools for solid tumors. GPA33 is highly expressed in most human colorectal cancers and has been verified as a diagnostic and therapeutic target. Here, we built an A33scFv-Fc antibody against GPA33 by fusing A33scFv to the Fc fragmen...

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Detalles Bibliográficos
Autores principales: Wei, Danfeng, Fan, Qing, Cai, Huawei, Yang, Hao, Wan, Lin, Li, Lin, Lu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454727/
https://www.ncbi.nlm.nih.gov/pubmed/26090413
http://dx.doi.org/10.1155/2015/505183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454727/
https://www.ncbi.nlm.nih.gov/pubmed/26090413
http://dx.doi.org/10.1155/2015/505183

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