The Flavonoid Apigenin Ameliorates Cisplatin-Induced Nephrotoxicity through Reduction of p53 Activation and Promotion of PI3K/Akt Pathway in Human Renal Proximal Tubular Epithelial Cells

Apigenin is a member of the flavone subclass of flavonoids present in fruits and vegetables. Apigenin has long been considered to have various biological activities, such as antioxidant, anti-inflammatory, and antitumorigenic properties, in various cell types. Cisplatin was known to exhibit cytotoxi...

Descripción completa

Detalles Bibliográficos
Autores principales: Ju, Sung Min, Kang, Jun Gue, Bae, Jun Sang, Pae, Hyun Ock, Lyu, Yeoung Su, Jeon, Byung Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454761/
https://www.ncbi.nlm.nih.gov/pubmed/26089934
http://dx.doi.org/10.1155/2015/186436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454761/
https://www.ncbi.nlm.nih.gov/pubmed/26089934
http://dx.doi.org/10.1155/2015/186436

Ejemplares similares