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Genetic and Epigenetic Modulation of Growth Hormone Sensitivity Studied With the IGF-1 Generation Test

CONTEXT: Like all hormones, GH has variable physiological effects across people. Many of these effects initiated by the binding of GH to its receptor (GHR) in target tissues are mediated by the expression of the IGF1 gene. Genetic as well as epigenetic variation is known to contribute to the individ...

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Detalles Bibliográficos
Autores principales:	Ouni, Meriem, Castell, Anne-Laure, Linglart, Agnès, Bougnères, Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2015
Materias:	JCEM Online: Advances in Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454803/ https://www.ncbi.nlm.nih.gov/pubmed/25835289 http://dx.doi.org/10.1210/jc.2015-1413

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