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Selection on noise constrains variation in a eukaryotic promoter
Genetic variation segregating within a species reflects the combined activities of mutation, selection, and genetic drift. In the absence of selection, polymorphisms are expected to be a random subset of new mutations; thus, comparing the effects of polymorphisms and new mutations provides a test fo...
Autores principales: | Metzger, Brian P. H., Yuan, David C., Gruber, Jonathan D., Duveau, Fabien, Wittkopp, Patricia J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455047/ https://www.ncbi.nlm.nih.gov/pubmed/25778704 http://dx.doi.org/10.1038/nature14244 |
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