Stimulation of soluble guanylyl cyclase protects against obesity by recruiting brown adipose tissue

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Obesity is characterized by a positive energy balance and expansion of white adipose tissue (WAT). In contrast, brown adipose tissue (BAT) combusts energy to produce heat. Here we show that a small molecule stimulator (BAY 41-8543) of soluble guanylyl cyclase (sGC), which produces the second messeng...

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Detalles Bibliográficos
Autores principales: Hoffmann, Linda S., Etzrodt, Jennifer, Willkomm, Lena, Sanyal, Abhishek, Scheja, Ludger, Fischer, Alexander W.C., Stasch, Johannes-Peter, Bloch, Wilhelm, Friebe, Andreas, Heeren, Joerg, Pfeifer, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455111/
https://www.ncbi.nlm.nih.gov/pubmed/26011238
http://dx.doi.org/10.1038/ncomms8235

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