A new arylbenzofuran derivative functions as an anti-tumour agent by inducing DNA damage and inhibiting PARP activity

We previously reported that 7-hydroxy-5, 4’-dimethoxy-2-arylbenzofuran (HDAB) purified from Livistona chinensis is a key active agent. The present study investigated the function and molecular mechanism of HDAB. HDAB treatment of cervical cancer cells resulted in S phase arrest and apoptosis, togeth...

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Detalles Bibliográficos
Autores principales: Chen, Hongbo, Zeng, Xiaobin, Gao, Chunmei, Ming, Pinghong, Zhang, Jianping, Guo, Caiping, Zhou, Lanzhen, Lu, Yin, Wang, Lijun, Huang, Laiqiang, He, Xiangjiu, Mei, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455115/
https://www.ncbi.nlm.nih.gov/pubmed/26041102
http://dx.doi.org/10.1038/srep10893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455115/
https://www.ncbi.nlm.nih.gov/pubmed/26041102
http://dx.doi.org/10.1038/srep10893

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