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Expanding the chemical space for natural products by Aspergillus-Streptomyces co-cultivation and biotransformation
Actinomycetes and filamentous fungi produce a wide range of bioactive compounds, with applications as antimicrobials, anticancer agents or agrochemicals. Their genomes contain a far larger number of gene clusters for natural products than originally anticipated, and novel approaches are required to...
Autores principales: | Wu, Changsheng, Zacchetti, Boris, Ram, Arthur F.J., van Wezel, Gilles P., Claessen, Dennis, Hae Choi, Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455117/ https://www.ncbi.nlm.nih.gov/pubmed/26040782 http://dx.doi.org/10.1038/srep10868 |
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