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Parallel fiber to Purkinje cell synaptic impairment in a mouse model of spinocerebellar ataxia type 27

Genetically inherited mutations in the fibroblast growth factor 14 (FGF14) gene lead to spinocerebellar ataxia type 27 (SCA27), an autosomal dominant disorder characterized by heterogeneous motor and cognitive impairments. Consistently, genetic deletion of Fgf14 in Fgf14(−/−) mice recapitulates sali...

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Detalles Bibliográficos
Autores principales:	Tempia, Filippo, Hoxha, Eriola, Negro, Giulia, Alshammari, Musaad A., Alshammari, Tahani K., Panova-Elektronova, Neli, Laezza, Fernanda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455242/ https://www.ncbi.nlm.nih.gov/pubmed/26089778 http://dx.doi.org/10.3389/fncel.2015.00205

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