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TonEBP suppresses adipogenesis and insulin sensitivity by blocking epigenetic transition of PPARγ2

TonEBP is a key transcription factor in cellular adaptation to hypertonic stress, and also in macrophage activation. Since TonEBP is involved in inflammatory diseases such as rheumatoid arthritis and atherosclerosis, we asked whether TonEBP played a role in adipogenesis and insulin resistance. Here...

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Detalles Bibliográficos
Autores principales: Ho Lee, Jun, Hee Lee, Hwan, Jin Ye, Byeong, Lee-Kwon, Whaseon, Youn Choi, Soo, Moo Kwon, Hyug
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455245/
https://www.ncbi.nlm.nih.gov/pubmed/26042523
http://dx.doi.org/10.1038/srep10937