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Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat

BACKGROUND: Fusarium head blight (FHB) and Septoria tritici blotch (STB) severely impair wheat production. With the aim to further elucidate the genetic architecture underlying FHB and STB resistance, we phenotyped 1604 European wheat hybrids and their 135 parental lines for FHB and STB disease seve...

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Autores principales: Mirdita, Vilson, Liu, Guozheng, Zhao, Yusheng, Miedaner, Thomas, Longin, C. Friedrich H., Gowda, Manje, Mette, Michael Florian, Reif, Jochen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455280/
https://www.ncbi.nlm.nih.gov/pubmed/26044734
http://dx.doi.org/10.1186/s12864-015-1628-8
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author Mirdita, Vilson
Liu, Guozheng
Zhao, Yusheng
Miedaner, Thomas
Longin, C. Friedrich H.
Gowda, Manje
Mette, Michael Florian
Reif, Jochen C.
author_facet Mirdita, Vilson
Liu, Guozheng
Zhao, Yusheng
Miedaner, Thomas
Longin, C. Friedrich H.
Gowda, Manje
Mette, Michael Florian
Reif, Jochen C.
author_sort Mirdita, Vilson
collection PubMed
description BACKGROUND: Fusarium head blight (FHB) and Septoria tritici blotch (STB) severely impair wheat production. With the aim to further elucidate the genetic architecture underlying FHB and STB resistance, we phenotyped 1604 European wheat hybrids and their 135 parental lines for FHB and STB disease severities and determined genotypes at 17,372 single-nucleotide polymorphic loci. RESULTS: Cross-validated association mapping revealed the absence of large effect QTL for both traits. Genomic selection showed a three times higher prediction accuracy for FHB than STB disease severity for test sets largely unrelated to the training sets. CONCLUSIONS: Our findings suggest that the genetic architecture is less complex and, hence, can be more properly tackled to perform accurate prediction for FHB than STB disease severity. Consequently, FHB disease severity is an interesting model trait to fine-tune genomic selection models exploiting beyond relatedness also knowledge of the genetic architecture. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12864-015-1628-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-44552802015-06-05 Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat Mirdita, Vilson Liu, Guozheng Zhao, Yusheng Miedaner, Thomas Longin, C. Friedrich H. Gowda, Manje Mette, Michael Florian Reif, Jochen C. BMC Genomics Research Article BACKGROUND: Fusarium head blight (FHB) and Septoria tritici blotch (STB) severely impair wheat production. With the aim to further elucidate the genetic architecture underlying FHB and STB resistance, we phenotyped 1604 European wheat hybrids and their 135 parental lines for FHB and STB disease severities and determined genotypes at 17,372 single-nucleotide polymorphic loci. RESULTS: Cross-validated association mapping revealed the absence of large effect QTL for both traits. Genomic selection showed a three times higher prediction accuracy for FHB than STB disease severity for test sets largely unrelated to the training sets. CONCLUSIONS: Our findings suggest that the genetic architecture is less complex and, hence, can be more properly tackled to perform accurate prediction for FHB than STB disease severity. Consequently, FHB disease severity is an interesting model trait to fine-tune genomic selection models exploiting beyond relatedness also knowledge of the genetic architecture. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12864-015-1628-8) contains supplementary material, which is available to authorized users. BioMed Central 2015-06-05 /pmc/articles/PMC4455280/ /pubmed/26044734 http://dx.doi.org/10.1186/s12864-015-1628-8 Text en © Mirdita et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Mirdita, Vilson
Liu, Guozheng
Zhao, Yusheng
Miedaner, Thomas
Longin, C. Friedrich H.
Gowda, Manje
Mette, Michael Florian
Reif, Jochen C.
Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat
title Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat
title_full Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat
title_fullStr Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat
title_full_unstemmed Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat
title_short Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat
title_sort genetic architecture is more complex for resistance to septoria tritici blotch than to fusarium head blight in central european winter wheat
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455280/
https://www.ncbi.nlm.nih.gov/pubmed/26044734
http://dx.doi.org/10.1186/s12864-015-1628-8
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