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Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat
BACKGROUND: Fusarium head blight (FHB) and Septoria tritici blotch (STB) severely impair wheat production. With the aim to further elucidate the genetic architecture underlying FHB and STB resistance, we phenotyped 1604 European wheat hybrids and their 135 parental lines for FHB and STB disease seve...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455280/ https://www.ncbi.nlm.nih.gov/pubmed/26044734 http://dx.doi.org/10.1186/s12864-015-1628-8 |
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author | Mirdita, Vilson Liu, Guozheng Zhao, Yusheng Miedaner, Thomas Longin, C. Friedrich H. Gowda, Manje Mette, Michael Florian Reif, Jochen C. |
author_facet | Mirdita, Vilson Liu, Guozheng Zhao, Yusheng Miedaner, Thomas Longin, C. Friedrich H. Gowda, Manje Mette, Michael Florian Reif, Jochen C. |
author_sort | Mirdita, Vilson |
collection | PubMed |
description | BACKGROUND: Fusarium head blight (FHB) and Septoria tritici blotch (STB) severely impair wheat production. With the aim to further elucidate the genetic architecture underlying FHB and STB resistance, we phenotyped 1604 European wheat hybrids and their 135 parental lines for FHB and STB disease severities and determined genotypes at 17,372 single-nucleotide polymorphic loci. RESULTS: Cross-validated association mapping revealed the absence of large effect QTL for both traits. Genomic selection showed a three times higher prediction accuracy for FHB than STB disease severity for test sets largely unrelated to the training sets. CONCLUSIONS: Our findings suggest that the genetic architecture is less complex and, hence, can be more properly tackled to perform accurate prediction for FHB than STB disease severity. Consequently, FHB disease severity is an interesting model trait to fine-tune genomic selection models exploiting beyond relatedness also knowledge of the genetic architecture. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12864-015-1628-8) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4455280 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-44552802015-06-05 Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat Mirdita, Vilson Liu, Guozheng Zhao, Yusheng Miedaner, Thomas Longin, C. Friedrich H. Gowda, Manje Mette, Michael Florian Reif, Jochen C. BMC Genomics Research Article BACKGROUND: Fusarium head blight (FHB) and Septoria tritici blotch (STB) severely impair wheat production. With the aim to further elucidate the genetic architecture underlying FHB and STB resistance, we phenotyped 1604 European wheat hybrids and their 135 parental lines for FHB and STB disease severities and determined genotypes at 17,372 single-nucleotide polymorphic loci. RESULTS: Cross-validated association mapping revealed the absence of large effect QTL for both traits. Genomic selection showed a three times higher prediction accuracy for FHB than STB disease severity for test sets largely unrelated to the training sets. CONCLUSIONS: Our findings suggest that the genetic architecture is less complex and, hence, can be more properly tackled to perform accurate prediction for FHB than STB disease severity. Consequently, FHB disease severity is an interesting model trait to fine-tune genomic selection models exploiting beyond relatedness also knowledge of the genetic architecture. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12864-015-1628-8) contains supplementary material, which is available to authorized users. BioMed Central 2015-06-05 /pmc/articles/PMC4455280/ /pubmed/26044734 http://dx.doi.org/10.1186/s12864-015-1628-8 Text en © Mirdita et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Mirdita, Vilson Liu, Guozheng Zhao, Yusheng Miedaner, Thomas Longin, C. Friedrich H. Gowda, Manje Mette, Michael Florian Reif, Jochen C. Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat |
title | Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat |
title_full | Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat |
title_fullStr | Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat |
title_full_unstemmed | Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat |
title_short | Genetic architecture is more complex for resistance to Septoria tritici blotch than to Fusarium head blight in Central European winter wheat |
title_sort | genetic architecture is more complex for resistance to septoria tritici blotch than to fusarium head blight in central european winter wheat |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455280/ https://www.ncbi.nlm.nih.gov/pubmed/26044734 http://dx.doi.org/10.1186/s12864-015-1628-8 |
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