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A study of the relationship between gender/age and apparent diffusion coefficient values in spleen of healthy adults using diffusion-weighted magnetic resonance imaging

BACKGROUND: Diffusion-weighted magnetic resonance imaging (DWI) systems are very effective in detecting strokes, and they also have shown significant promise in the detection of fibrosis and cirrhosis of the liver. However, such systems have the disadvantages of poor reproducibility and noise, which...

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Autores principales: Nazarlou, Ali Kiani, Abdolmohammadi, Jamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Electronic physician 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455294/
https://www.ncbi.nlm.nih.gov/pubmed/26052412
http://dx.doi.org/10.14661/2015.1005-1009
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author Nazarlou, Ali Kiani
Abdolmohammadi, Jamil
author_facet Nazarlou, Ali Kiani
Abdolmohammadi, Jamil
author_sort Nazarlou, Ali Kiani
collection PubMed
description BACKGROUND: Diffusion-weighted magnetic resonance imaging (DWI) systems are very effective in detecting strokes, and they also have shown significant promise in the detection of fibrosis and cirrhosis of the liver. However, such systems have the disadvantages of poor reproducibility and noise, which can diminish the accuracy of the apparent diffusion coefficients (ADCs) provided by the DWI process. The main aim of this study was to determine the relationship between the age and gender of healthy adults in terms of the ADC values of the spleen measured by DWI. METHODS: Sixty-nine subjects selected for this study from people who were referred to the Tabesh Medical Imaging Center in Tabriz, Iran, in 2013. Each subject underwent echo-planar DWI for her or his ADC values of the spleen with b-values of 50, 400, and 800 s/mm2, and the resulting ADC values were evaluated. RESULTS: No significant differences were observed in ADC values of the spleen among the female and male participants or those from various ages (P>0.05). CONCLUSIONS: Based on the findings of this study, it was concluded that the effect of age and gender on the spleen’s ADC values can be omitted from the spleen-diagnosis procedure. In other words, the spleen’s ADC values are not related to the age or the gender of healthy adults.
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spelling pubmed-44552942015-06-05 A study of the relationship between gender/age and apparent diffusion coefficient values in spleen of healthy adults using diffusion-weighted magnetic resonance imaging Nazarlou, Ali Kiani Abdolmohammadi, Jamil Electron Physician Original Article BACKGROUND: Diffusion-weighted magnetic resonance imaging (DWI) systems are very effective in detecting strokes, and they also have shown significant promise in the detection of fibrosis and cirrhosis of the liver. However, such systems have the disadvantages of poor reproducibility and noise, which can diminish the accuracy of the apparent diffusion coefficients (ADCs) provided by the DWI process. The main aim of this study was to determine the relationship between the age and gender of healthy adults in terms of the ADC values of the spleen measured by DWI. METHODS: Sixty-nine subjects selected for this study from people who were referred to the Tabesh Medical Imaging Center in Tabriz, Iran, in 2013. Each subject underwent echo-planar DWI for her or his ADC values of the spleen with b-values of 50, 400, and 800 s/mm2, and the resulting ADC values were evaluated. RESULTS: No significant differences were observed in ADC values of the spleen among the female and male participants or those from various ages (P>0.05). CONCLUSIONS: Based on the findings of this study, it was concluded that the effect of age and gender on the spleen’s ADC values can be omitted from the spleen-diagnosis procedure. In other words, the spleen’s ADC values are not related to the age or the gender of healthy adults. Electronic physician 2015-03-01 /pmc/articles/PMC4455294/ /pubmed/26052412 http://dx.doi.org/10.14661/2015.1005-1009 Text en © 2015 The Authors This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (http://creativecommons.org/licenses/by-nc-nd/3.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Original Article
Nazarlou, Ali Kiani
Abdolmohammadi, Jamil
A study of the relationship between gender/age and apparent diffusion coefficient values in spleen of healthy adults using diffusion-weighted magnetic resonance imaging
title A study of the relationship between gender/age and apparent diffusion coefficient values in spleen of healthy adults using diffusion-weighted magnetic resonance imaging
title_full A study of the relationship between gender/age and apparent diffusion coefficient values in spleen of healthy adults using diffusion-weighted magnetic resonance imaging
title_fullStr A study of the relationship between gender/age and apparent diffusion coefficient values in spleen of healthy adults using diffusion-weighted magnetic resonance imaging
title_full_unstemmed A study of the relationship between gender/age and apparent diffusion coefficient values in spleen of healthy adults using diffusion-weighted magnetic resonance imaging
title_short A study of the relationship between gender/age and apparent diffusion coefficient values in spleen of healthy adults using diffusion-weighted magnetic resonance imaging
title_sort study of the relationship between gender/age and apparent diffusion coefficient values in spleen of healthy adults using diffusion-weighted magnetic resonance imaging
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455294/
https://www.ncbi.nlm.nih.gov/pubmed/26052412
http://dx.doi.org/10.14661/2015.1005-1009
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