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Inhibitory effects of Mycoepoxydiene on macrophage foam cell formation and atherosclerosis in ApoE-deficient mice

BACKGROUND: Mycoepoxydiene (MED) is a polyketide that can be isolated from a marine fungus and is associated with various activities, including antitumor and anti-inflammatory functions. However, its effects on atherosclerosis remain unknown. Macrophage-derived foam cells play crucial roles in the i...

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Detalles Bibliográficos
Autores principales: Xia, Xiaochun, Li, Yang, Su, Qiang, Huang, Zhengrong, Shen, Yuemao, Li, Weihua, Yu, Chundong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455339/
https://www.ncbi.nlm.nih.gov/pubmed/26045945
http://dx.doi.org/10.1186/s13578-015-0017-y