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Exploring the effects of cell seeding density on the differentiation of human pluripotent stem cells to brain microvascular endothelial cells

BACKGROUND: Brain microvascular-like endothelial cells (BMECs) derived from human pluripotent stem cells (hPSCs) have significant promise as tools for drug screening and studying the structure and function of the BBB in health and disease. The density of hPSCs is a key factor in regulating cell fate...

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Detalles Bibliográficos
Autores principales: Wilson, Hannah K, Canfield, Scott G, Hjortness, Michael K, Palecek, Sean P, Shusta, Eric V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455681/
https://www.ncbi.nlm.nih.gov/pubmed/25994964
http://dx.doi.org/10.1186/s12987-015-0007-9